BSB, Route 1070
Departments of Microbiology & Immunology and Pathology
|PhD | 1976 | Duke University|
|MS | 1973 | University of North Dakota|
|BA | 1971 | University of Montana|
Biological, genetic, and molecular mechanisms of HIV and mouse leukemia virus pathogenesis.
Dr. Cloyd's research focuses on understanding the molecular mechanisms underlying the pathogenesis of HIV and retroviruses that cause leukemia. His current work explores host genetic resistance to HIV, how HIV causes AIDS and shuts down into latency, and how MCF murine leukemia viruses cause transformation. His studies of the molecular mechanisms of the transformation by murine leukemia viruses examine the effects of retroviral infection and gene products on membrane-mediated signal transduction processes and mechanisms of activation of host genes. His HIV studies are aimed at identifying and characterizing host genetic resistance/susceptibility genes influencing HIV infection, molecular mechanisms of HIV latency, functional properties of latently infected normal CD4 lymphocytes, functions of and interplay between HIV genes and gene products in determining viral biological properties, the mechanism by which HIV causes depletion of CD4 lymphocytes, and development of new diagnostics for HIV.
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