Faculty

Michael McGinnis, Ph.D.

Professor
mmcginni@utmb.edu
John Sealy Annex, Route 0740
Departments of Pathology, Dermatology and Microbiology & Immunology
Phone: (409)747-0603
Fax:

Education:	Ph.D. | 1969 | Iowa State University, Ames, IA
	B.S. | 1966 | California State Polytechnic University, San Luis Obispo, CA

Overview

Molecular evolution and taxonomy of fungi.

Research Interests

My primary area of research deals with the pathogenesis of indoor mould-related health problems. In addition, the effect of modeled low shear microgravity upon fundamental processes of yeasts is of special interest.

Research activities are oriented towards the integration of anamorphic, teleomorphic and holomorphic species concepts into a dynamic classification system for the dematiaceous moulds that grow within the indoor environment. This will be built upon gene sequence data and derived phylogenic relationships. Morphogenesis, conidiogenesis and molecular tools will provide a clearer understanding of the basic biology of this group of microorganisms. Such an understanding will be useful for investigating pathogenesis when these fungi serve as opportunistic pathogens via a source of allergens and mycotoxins.

Microgravity research involves studying the effect of modeled microgravity upon Saccharomyces cerevisiae and Candida albicans gene expression following their growth in a bioreactor, during a space shuttle flight, and on the space station. The effect of microgravity upon intracellular evolution, sensitivity of fungi to antifungal drugs, and basic cellular developmental processes will be characterized.

Recent Publications

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