Faculty

David W Niesel, PhDDavid W Niesel, PhD

Lawrence E. Etheridge, Jr. Professor
Chief Research Officer
Vice President and Dean, Graduate School of Biomedical Sciences

In vivo virulence gene expression; bacterial pathogenesis; functional genomics, microgravity environments

dniesel@utmb.edu
Levin Hall 3.316E
Phone: (409) 772-0758

Post-Baccalaureate Research Education (PREP) Program

Education:

PhD | 1980 | North Carolina State University
BA | 1975 | Quinnipiac College


Overview:
In vivo virulence gene expression; bacterial pathogenesis; functional genomics, microgravity environments.

Research Interests

Dr. Niesel’s laboratory is investigating in vivo models of gene/protein expression by the respiratory pathogen Streptococcus pneumoniae and facultative intracellular bacteria (Francisella tularensis, Shigella flexneri, Salmonella typhimurium). In addition, his research group is investigating alterations in gene/ protein expression and alterations to the virulence potential of S. pneumoniae in a low shear environments. He has had multiple experiments performed on the space shuttle and on the International Space Station. The Niesel lab is also interested in the initial responses of host cells to bacterial pathogens, which lead to new initiation of cellular signaling and the host immune response.

Recent Publications

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