Students

Doug Widman

Major: Virology
Joined program in 2006

Mentor: Dr. Peter Mason

Research Description: My work is designed to identify key mutations that enhance the growth of our novel Flavivirus vaccine candidate and the effect that this increased growth has on the immune response. I also am studying the exact mechanism of action of the vaccine; in particular the role of type I interferon plays in the immunity elicited from vaccination. Studies are being done to identify the precise cells inducing the interferon response, producing immunogen, and presenting immunogen using multiple animal models. With an aim to induce a stronger immune response and thereby increase efficacy, we are employing different viral “coats” with enhanced binding characteristics. In addition to this, work is being done on the safety and stability of the vaccine, with careful consideration of the environment in which Flavivirus vaccine are most utilized.

Hometown: Detroit, MI
Education: Oakland University (BS in Biological Sciences)
Hobbies: Automobiles, disc golf
Contact:  dgwidman@utmb.edu

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