Professor, Microbiology & Immunology and Pathology
Analysis of unique murine models of inflammatory bowel disease.
|Visiting PhD Student | 1988-1990 | Tufts University School of Medicine, Boston, MA|
|PhD | 1990 | Shandong University, P.R. China|
|MSc | 1985 | Shandong University, P.R. China|
|BSc | 1982 | Shandong University, P.R. China|
The host and microbiota have evolved mechanisms for coexistence over millions of years. Accumulating evidence indicates that a dynamic mutualism between the host and the commensal microbiota has important implications for health, and microbial colonization contributes to the maintenance of intestinal immune homeostasis. However, alterations in communication between the mucosal immune system and gut microbial communities have been implicated as the core defect that leads to development of chronic intestinal inflammation and cancer as well as other diseases, such as diabetes, obesity etc. Dr. Yingzi Cong’s basic research programs focus on investigating host immune system‐microbiome interaction in the intestines, pathogenesis of inflammatory bowel disease, and development of mucosal vaccines, which are based on the analysis of unique murine models of inflammatory bowel disease using a battery of reagents that have been developed recently. A number of research projects are underway in his laboratory and these NIH funded studies involve a number of significant collaborations both at UTMB as well as with other Universities and Research Institutes. Specifically, individual projects include: