MinKyung Yi, PhD
Professor
Department of Microbiology & Immunology
Phone: (409) 772-2338
Fax: (409) 772-5065
Email:
miyi@utmb.edu
Education: PhD, 1997, Cancer Research Institute, Kanazawa University, Japan
MS, 1992, Pohang Institute of Science and Technology, Life Science, Korea
BS, 1990, Seoul National Unversity, College of Pharmacy, Korea
Overview: Molecular
Biology of Hepatitis C Virus, Virus-Host Interactions Related to HCC (hepatocellular carcinoma) and Metabolic Diseases
Research Interests
Hepatitis C virus (HCV) is a small, enveloped, positiveâ€stranded RNA virus belonging to the family Flaviviridae. HCV often leads to serious liver diseases, including liver fibrosis, cirrhosis and hepatocellular carcinoma. HCV infection has
also been linked to metabolic diseases, such as NAFLD (non alcoholic fatty liver disease) and type 2 diabetes. Our current research focuses on two major areas that are least understood. First, we are studying the mechanism of hepatitis C virus assembly
process to understand how it could form lipoviro particles (virus-lipoprotein hybrid), which likely allow it to avoid host immune detection leading to chronic infection. Second, we are studying virus host interactions involved in HCV-induced pathogenesis,
including liver fibrosis and hepatocellular carcinoma.
Recent Publications
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