Nigel Bourne, PhD
Professor, Pediatrics and Microbiology & Immunology
Departments of Pediatric Virology and Microbiology & Immunology
Phone: (409) 747-8144
Education: PhD, University of Wales (Cardiff) Institute of Science and Technology
Overview: In vivo models used to explore the pathogenesis of infectious disease focusing on genital and
neonatal Herpes simplex viral infection
In my laboratory we are interested in the development of in vivo models to explore the pathogenesis of infectious diseases and their use
to evaluate strategies for disease prevention and treatment.
One of our principle areas of interest has been genital and
neonatal Herpes simplex virus infection. We are continuing to explore
the pathogenesis of these infections as well conducting research on
vaccines and chemoprophylactics for their prevention and antiviral
agents for their treatment.
As part of our research on the use of chemoprophylactics to protect
the vaginal epithelium we have also begun studies with an important
bacterial pathogen Chlamydia trachomatis. In addition we have used in
vivo models to explore a number of congenital infections of clinical
importance including cytomegalovirus and toxoplasmosis.
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