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Faculty

MinKyung Yi, PhDMinKyung Yi, PhD

Professor, Microbiology & Immunology
Replication of hepatitis A virus and hepatitis C virus


miyi@utmb.edu
MRB 4.142H, Route 1019
Department of Microbiology & Immunology
Phone: (409) 772-2338
Fax: (409) 772-5065

Education:

PhD | 1997 | Cancer Research Institute, Kanazawa University, Japan
MS | 1992 | Pohang Institute of Science and Technology, Life Science, Korea
BS | 1990 | Seoul National Unversity, College of Pharmacy, Korea


Overview:
Molecular Biology of Hepatitis C Virus, Virus‐Host Interactions Related to HCC (hepatocellular carcinoma) and Metabolic Diseases

Research Interests

Hepatitis C virus (HCV) is a small, enveloped, positive‐stranded RNA virus belonging to the family Flaviviridae. HCV often leads to serious liver diseases, including liver fibrosis, cirrhosis and hepatocellular carcinoma. HCV infection has also been linked to metabolic diseases, such as NAFLD (non alcoholic fatty liver disease) and type 2 diabetes. Our current research focuses on two major areas that are least understood. First, we are studying the mechanism of hepatitis C virus assembly process to understand how it could form lipoviro particles (virus‐lipoprotein hybrid), which likely allow it to avoid host immune detection leading to chronic infection. Second, we are studying virus host interactions involved in HCV‐induced pathogenesis, including liver fibrosis and hepatocellular carcinoma.

Recent Publications

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